Dr. Savino is a graduate of Manhattan College and received his medical degree from the University Of Bologna School Of Medicine. He completed his ophthalmology residency at Georgetown University Medical Center and was a Heed Fellow in Neuro-Ophthalmology at Bascom Palmer Eye Institute at the University of Miami.

Dr. Savino was Director of the Neuro-Ophthalmology Service at Wills Eye Hospital, where he was a staff member since 1976, and had served as Chairman of the Department of Ophthalmology at the Graduate Hospital in Philadelphia since 1980. He was also Professor of Ophthalmology, Neurology and Neurosurgery at Thomas Jefferson University.

Dr. Savino has been the principal investigator on several studies funded by NIH grants and has published more than 200 articles in scientific journals including on the topics of optic nerve, optic neuritis, ischemic optic neuropathy, papilledema, pseudotumor cerebri, giant cell arteritis, thyroid eye disease, double vision, visual field defects, and brain tumor. He has co-authored two textbooks of neuro-ophthalmology and has authored or co-authored more than 40 book chapters. He serves as a scientific reviewer for 14 scientific journals and as an editor of four other journals.

Dr. Savino has lectured extensively around the world and delivered 20 named lectureships. He is the recipient of numerous awards, including honors from the American Academy of Ophthalmology, The Chicago Ophthalmic Society and the Philadelphia Ophthalmic Society and has been voted Best Teacher of the Year at Wills Eye Hospital three times. He was named one of the 100 best ophthalmologists in the United States by Ophthalmology Times and is consistently included in Philadelphia Magazine's Best Doctors list.